In the field of pharmaceutical synthesis, silylation reaction is an important step in the synthesis of many key pharmaceutical intermediates. As an efficient silane based reagent, hexamethyldisilazane IOTA 011 is providing strong support for the synthesis of pharmaceutical products such as antibiotics and anticancer drugs.
Core advantages of IOTA 011
Efficient Silylation:
IOTA 011 can efficiently introduce silyl groups, protect active hydroxyl groups, and improve reaction selectivity and yield in the synthesis of drugs such as amikacin, penicillin, cephalosporin, and fluorouracil.
High purity and stability:
The product purity is ≥ 99.0%, and the impurity content is extremely low (hexamethyldisiloxane ≤ 0.5%, trimethylsilanol ≤ 0.3%), ensuring the efficiency and consistency of the reaction.
Multifunctionality:
In addition to pharmaceutical synthesis, IOTA 011 can also serve as an antibiotic hydroxyl protectant, widely used in drug development and production.
Application scenarios
Antibiotic synthesis: used for intermediate synthesis of antibiotics such as penicillin and cephalosporin;
Anti cancer drugs: used for the silylation reaction of anticancer drugs such as fluorouracil;
Drug development: As a hydroxyl protecting agent, it improves the efficiency and purity of drug synthesis.
Conclusion:
IOTA 011 is not only an efficient protective agent in pharmaceutical synthesis, but also an important force in promoting technological upgrading in the pharmaceutical industry. Choosing IOTA 011 means choosing efficiency, purity, and reliability!

Product specifications:
Appearance: Colorless and transparent liquid
Density (25 ℃): 0.774 g/cm ³
Refractive index (20 ℃): 1.4069-1.4089
Melting point:- 78℃
Flash point: 27 ℃
Boiling point: 125 ℃
Water solubility: Reacts
Content (≥): 99.0%
Hexamethyldisiloxane content (≤): 0.5%
Trimethylsilanol content (≤): 0.3%
Chlorine content (≤): 50ppm
Packaging and Storage:
25kg/drum or 200kg/drum packaging, stored in a cool and dry place, away from direct sunlight, shelf life of 12 months.