IOTA 5160 is a highly reactive chloromethyl-substituted chlorosilane monomer containing two Si–Cl bonds and a chloromethyl (–CH₂Cl) functional group. It can serve as a key building block for the synthesis of various pharmaceutical intermediates and active ingredients. With its high purity and controllable reactivity, it is a reliable silicon-based raw material for medicinal chemistry research and production.

Key Features

• Dual Functional Groups: Contains both Si–Cl bonds and a chloromethyl group, enabling participation in nucleophilic substitution, silylation, cyclization, and other reactions.

• High Reactivity: Suitable for constructing complex molecular frameworks, improving synthesis efficiency.

• Volatile Transparent Liquid: Facilitates metering, transfer, and purification processes.

• Good Batch-to-Batch Consistency: Meets the stringent raw material uniformity requirements of the pharmaceutical industry.

Technical Specifications

Main Applications (Pharmaceutical Field)

• Pharmaceutical Intermediate Synthesis: Used as a silylation reagent or structural fragment for the construction of antiviral, anticancer, and other drug molecules.

• Introduction of Active Functional Groups: Introduces modifiable sites into molecules via the chloromethyl group or Si–Cl bonds.

• Preparation of Heterocyclic Compounds: Participates in cyclization reactions to synthesize silicon- or chlorine-containing heterocyclic intermediates.

Why Choose IOTA 5160

In pharmaceutical R&D and production, the purity and reaction selectivity of intermediates are critically important. With its well-defined molecular structure, stable physicochemical properties, and flexible reaction pathways, IOTA 5160 serves as a reliable tool for medicinal chemists constructing complex molecules.

For samples, technical data, or synthetic route recommendations, please contact us to advance intermediate development for innovative drugs.